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A20 deficiency in multipotent progenitors perturbs quiescence of hematopoietic stem cells.
Stem Cell Res. 2018 Dec;33:199-205. doi: 10.1016/j.scr.2018.10.020. Epub 2018 Oct 31.
Stem Cell Res. 2018.
PMID: 30445411
Free PMC article.
A20 deficiency in hematopoietic stem cells causes lymphopenia and myeloproliferation due to elevated Interferon-γ signals.
Nakagawa MM, Rathinam CV.
Nakagawa MM, et al.
Sci Rep. 2019 Sep 2;9(1):12658. doi: 10.1038/s41598-019-49038-8.
Sci Rep. 2019.
PMID: 31477755
Free PMC article.
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Physiological Srsf2 P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice.
Kon A, Yamazaki S, Nannya Y, Kataoka K, Ota Y, Nakagawa MM, Yoshida K, Shiozawa Y, Morita M, Yoshizato T, Sanada M, Nakayama M, Koseki H, Nakauchi H, Ogawa S.
Kon A, et al. Among authors: nakagawa mm.
Blood. 2018 Feb 8;131(6):621-635. doi: 10.1182/blood-2017-01-762393. Epub 2017 Nov 16.
Blood. 2018.
PMID: 29146882
Free PMC article.
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Constitutive Activation of the Canonical NF-κB Pathway Leads to Bone Marrow Failure and Induction of Erythroid Signature in Hematopoietic Stem Cells.
Nakagawa MM, Rathinam CV.
Nakagawa MM, et al.
Cell Rep. 2018 Nov 20;25(8):2094-2109.e4. doi: 10.1016/j.celrep.2018.10.071.
Cell Rep. 2018.
PMID: 30463008
Free PMC article.
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Constitutive Activation of NF-κB Pathway in Hematopoietic Stem Cells Causes Loss of Quiescence and Deregulated Transcription Factor Networks.
Nakagawa MM, Chen H, Rathinam CV.
Nakagawa MM, et al.
Front Cell Dev Biol. 2018 Oct 30;6:143. doi: 10.3389/fcell.2018.00143. eCollection 2018.
Front Cell Dev Biol. 2018.
PMID: 30425986
Free PMC article.
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Lack of the ubiquitin-editing enzyme A20 results in loss of hematopoietic stem cell quiescence.
Nakagawa MM, Thummar K, Mandelbaum J, Pasqualucci L, Rathinam CV.
Nakagawa MM, et al.
J Exp Med. 2015 Feb 9;212(2):203-16. doi: 10.1084/jem.20132544. Epub 2015 Jan 26.
J Exp Med. 2015.
PMID: 25624445
Free PMC article.
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Slicer Endonuclease Argonaute 2 Is a Negative Regulator of Hematopoietic Stem Cell Quiescence.
Lu K, Nakagawa MM, Thummar K, Rathinam CV.
Lu K, et al. Among authors: nakagawa mm.
Stem Cells. 2016 May;34(5):1343-53. doi: 10.1002/stem.2302. Epub 2016 Mar 28.
Stem Cells. 2016.
PMID: 26850790
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